Trump is not supporting TPP.
So the only way now to go for multilateral trade deals will be the China lead RCEP and FTAPP with the One Belt One Road - that potentially will have Economic Returns of $100 trillion in trade revenue.
This will far replace the loss in TPP.
US leadership in trade will lose its significance as Trump is trying to restrict :-
(1) Trade
(2) Investment
(3) People flow - and thus restrict travel
ASEAN can work together to increase tourism numbers, says PM Lee